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Anti-Pregnancy zone protein PZP Antibody

Boster Bio Anti-Pregnancy zone protein PZP Antibody catalog # A05041. Tested in ELISA, WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

Pregnancy zone protein; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6; PZP; CPAMD6;

Gene Name

PZP

UniProt

P20742

Host

Rabbit

Reactivity

Human

Immunogen

Synthesized peptide derived from human protein at AA range: 1301-1350

Clonality

Polyclonal

Tissue Specificity

Plasma. Prominent constituent of late- pregnancy sera.

Applications

WB, ELISA

Purification

PZP antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced) . Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.

Molecular Weight

163863 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A05041

Product MSDS

https://www.bosterbio.com/msds?sku=A05041

Fragment

IgG

Other Gene Names

Pregnancy zone protein

Subcellular Location

Secreted.

Protein Name

Pregnancy zone protein

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