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Anti-LECT1 CNMD Antibody

Boster Bio Anti-LECT1 CNMD Antibody catalog # A32278-1. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Leukocyte cell-derived chemotaxin 1 ; Chondromodulin

Gene Name

CNMD

UniProt

O75829

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human protein at AA range: 150-230

Clonality

Polyclonal

Tissue Specificity

Detected in cartilage and cardiac valves (at protein level) . Detected in the laminae fibrosa, spongiosa and ventricularis layers of normal cardiac valves (at protein level) . Expression is decreased cardiac valves of patients with valvular heart disease (at protein level) . Weakly expressed in chondrosarcoma.

Applications

WB, ELISA

Purification

LECT1 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

Bifunctional growth regulator that stimulates the growth of cultured chondrocytes in the presence of basic fibroblast growth factor (FGF) but inhibits the growth of cultured vascular endothelial cells. May contribute to the rapid growth of cartilage and vascular invasion prior to the replacement of cartilage by bone during endochondral bone development. Inhibits in vitro tube formation and mobilization of endothelial cells. Plays a role as antiangiogenic factor in cardiac valves to suppress neovascularization.

Molecular Weight

37102 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Leukocyte cell-derived chemotaxin 1

Subcellular Location

Chondromodulin-1: Secreted, extracellular space, extracellular matrix. Accumulated in the inter- territorial matrix of cartilage.

Protein Name

Leukocyte cell-derived chemotaxin 1

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