Anti-CLC2D CLEC2D Antibody
Boster Bio Anti-CLC2D CLEC2D Antibody catalog # A06635. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
C-type lectin domain family 2 member D; Lectin-like NK cell receptor; Lectin-like transcript 1; LLT-1; Osteoclast inhibitory lectin; CLEC2D; CLAX, LLT1, OCIL;
Gene Name
CLEC2D
UniProt
Q9UHP7
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human protein at AA range: 40-120
Clonality
Polyclonal
Tissue Specificity
Detected in peripheral blood leukocytes, osteoblasts, lymph node, thymus and spleen. Isoform 1, isoform 2 and isoform 4 are expressed in T- and B-lymphocytes, and at lower levels in NK cells. They are also expressed in B-cell lines and LPS-matured monocyte-derived dendritic cells.
Applications
WB, ELISA
Purification
CLC2D antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Form
Liquid
Function
Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis (PubMed:20843815, PubMed:16339513) . Inhibits osteoclast formation (PubMed:14753741, PubMed:15123656) . Inhibits bone resorption (PubMed:14753741) . Modulates the release of interferon-gamma (PubMed:15104121) . Binds high molecular weight sulfated glycosaminoglycans (PubMed:15123656) .
Molecular Weight
21849 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
C-type lectin domain family 2 member D
Subcellular Location
Cell membrane
Protein Name
C-type lectin domain family 2 member D
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