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Anti-Legumain LGMN Antibody

Boster Bio Anti-Legumain LGMN Antibody catalog # A06476. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Legumain;3.4.22.34; Asparaginyl endopeptidase; Protease, cysteine 1; LGMN; PRSC1;

Gene Name

LGMN

UniProt

Q99538

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human protein at AA range: 60-140

Clonality

Polyclonal

Tissue Specificity

Ubiquitous. Particularly abundant in kidney, heart and placenta.

Applications

WB, ELISA

Purification

LGMN antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation (By similarity) . May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system.

Molecular Weight

49411 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Legumain

Subcellular Location

Lysosome .

Protein Name

Legumain

Frequently Asked Questions

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