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Anti-PTN14 PTPN14 Antibody

Boster Bio Anti-PTN14 PTPN14 Antibody catalog # A03313. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Tyrosine-protein phosphatase non-receptor type 14;3.1.3.48; Protein-tyrosine phosphatase pez; PTPN14; PEZ, PTPD2;

Gene Name

PTPN14

UniProt

Q15678

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Tissue Specificity

Ubiquitous.

Applications

WB, ELISA

Purification

PTN14 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

Protein tyrosine phosphatase which may play a role in the regulation of lymphangiogenesis, cell-cell adhesion, cell- matrix adhesion, cell migration, cell growth and also regulates TGF-beta gene expression, thereby modulating epithelial- mesenchymal transition. Mediates beta-catenin dephosphorylation at adhesion junctions. Acts as a negative regulator of the oncogenic property of YAP, a downstream target of the hippo pathway, in a cell density-dependent manner. May function as a tumor suppressor.

Molecular Weight

135261 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Tyrosine-protein phosphatase non-receptor type 14

Subcellular Location

Cytoplasm. Cytoplasm, cytoskeleton . Nucleus. Translocation into the nucleus is associated with induction of cell proliferation. Partially colocalized with actin filaments at the plasma membrane.

Protein Name

Tyrosine-protein phosphatase non-receptor type 14

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