Anti-FLRT2 Antibody

Boster Bio Anti-FLRT2 Antibody catalog # A08505. Tested in ELISA, WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

Leucine-rich repeat transmembrane protein FLRT2; Fibronectin-like domain-containing leucine-rich transmembrane protein 2; FLRT2; KIAA0405; UNQ232/PRO265;

Gene Name

FLRT2

UniProt

O43155

Host

Rabbit

Reactivity

Human

Immunogen

Synthesized peptide derived from human protein at AA range: 170-250

Clonality

Polyclonal

Tissue Specificity

Expressed in pancreas, skeletal muscle, brain, and heart.

Applications

WB, ELISA

Purification

FLRT2 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

Functions in cell-cell adhesion, cell migration and axon guidance. Mediates cell-cell adhesion via its interactions with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells. May play a role in the migration of cortical neurons during brain development via its interaction with UNC5D. Mediates axon growth cone collapse and plays a repulsive role in neuron guidance via its interaction with UNC5D, and possibly also other UNC-5 family members. Plays a role in fibroblast growth factor-mediated signaling cascades. Required for normal organization of the cardiac basement membrane during embryogenesis, and for normal embryonic epicardium and heart morphogenesis.