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Anti-Tyrosine-protein kinase RYK RYK Antibody

Selected Variant

A07225

Size: 100 µL

Boster Bio Anti-Tyrosine-protein kinase RYK RYK Antibody catalog # A07225. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Tyrosine-protein kinase RYK ;2.7.10.1

Gene Name

RYK

UniProt

P34925

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from human protein at AA range: 150-230

Clonality

Polyclonal

Tissue Specificity

Observed in all the tissues examined.

Applications

WB, ELISA

Purification

RYK antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C- terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development.

Molecular Weight

67815 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Tyrosine-protein kinase RYK

Subcellular Location

Membrane ; Single-pass type I membrane protein . Nucleus . Cytoplasm . In cells that have undergone neuronal differentiation, the C-terminal cleaved part is translocated from the cytoplasm to the nucleus. .

Protein Name

Tyrosine-protein kinase RYK

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