Anti-Tyrosine-protein kinase RYK RYK Antibody
Boster Bio Anti-Tyrosine-protein kinase RYK RYK Antibody catalog # A07225. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Tyrosine-protein kinase RYK ;2.7.10.1
Gene Name
RYK
UniProt
P34925
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human protein at AA range: 150-230
Clonality
Polyclonal
Tissue Specificity
Observed in all the tissues examined.
Applications
WB, ELISA
Purification
RYK antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Form
Liquid
Function
May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C- terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development.
Molecular Weight
67815 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Tyrosine-protein kinase RYK
Subcellular Location
Membrane ; Single-pass type I membrane protein . Nucleus . Cytoplasm . In cells that have undergone neuronal differentiation, the C-terminal cleaved part is translocated from the cytoplasm to the nucleus. .
Protein Name
Tyrosine-protein kinase RYK
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