Anti-PAPP1 PAPPA Antibody
Boster Bio Anti-PAPP1 PAPPA Antibody catalog # A04283. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Pappalysin-1;3.4.24.79; Insulin-like growth factor-dependent IGF-binding protein 4 protease; IGF-dependent IGFBP-4 protease; IGFBP-4ase; Pregnancy-associated plasma protein A; PAPP-A; PAPPA;
Gene Name
PAPPA
UniProt
Q13219
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human protein at AA range: 30-110
Clonality
Polyclonal
Tissue Specificity
High levels in placenta and pregnancy serum. In placenta, expressed in X cells in septa and anchoring villi, and in syncytiotrophoblasts in the chorionic villi. Lower levels are found in a variety of other tissues including kidney, myometrium, endometrium, ovaries, breast, prostate, bone marrow, colon, fibroblasts and osteoblasts.
Applications
WB, ELISA
Purification
PAPP1 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Form
Liquid
Function
Metalloproteinase which specifically cleaves IGFBP-4 and IGFBP-5, resulting in release of bound IGF. Cleavage of IGFBP-4 is dramatically enhanced by the presence of IGF, whereas cleavage of IGFBP-5 is slightly inhibited by the presence of IGF.
Molecular Weight
180973 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Pappalysin-1
Subcellular Location
Secreted
Protein Name
Pappalysin-1
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