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Anti-CRTAM Antibody

Boster Bio Anti-CRTAM Antibody catalog # A08105. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Cytotoxic and regulatory T-cell molecule; Class-I MHC-restricted T-cell-associated molecule; CD355; CRTAM

Gene Name

CRTAM

UniProt

O95727

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from human protein at AA range: 260-340

Clonality

Polyclonal

Tissue Specificity

In the immune system, expression is restricted to activated class-I MHC-restricted cells, including NKT and CD8 cells. Strongly expressed in spleen, thymus, small intestine, peripheral blood leukocyte, and in Purkinje neurons in cerebellum. Expressed at much lower levels in testis, ovary, colon, lung and lymphoid tissues.

Applications

WB, ELISA

Purification

CRTAM antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo.

Molecular Weight

44641 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Cytotoxic and regulatory T-cell molecule

Subcellular Location

Membrane ; Single-pass type I membrane protein .

Protein Name

Cytotoxic and regulatory T-cell molecule

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