Anti-Transcription factor MafG MAFG Antibody

Boster Bio Anti-Transcription factor MafG MAFG Antibody catalog # A04636-1. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Transcription factor MafG; V-maf musculoaponeurotic fibrosarcoma oncogene homolog G; hMAF; MAFG;

Gene Name

MAFG

UniProt

O15525

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Tissue Specificity

Highly expressed in skeletal muscle. Also expressed in heart and brain.

Applications

WB, ELISA

Purification

MAFG antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves (PubMed:11154691) . However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins, such as NFE2, NFE2L1 and NFE2L2, and recruiting them to specific DNA-binding sites (PubMed:8932385, PubMed:9421508, PubMed:11154691) . Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NFE2L2 transcription factor (PubMed:11154691) . Transcription factor, component of erythroid-specific transcription factor NFE2L2 (PubMed:11154691) . Activates globin gene expression when associated with NFE2L2 (PubMed:11154691) . May be involved in signal transduction of extracellular H (+) (By similarity) .