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Anti-CLC5A CLEC5A Antibody

Boster Bio Anti-CLC5A CLEC5A Antibody catalog # A07873. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

C-type lectin domain family 5 member A; C-type lectin superfamily member 5; Myeloid DAP12-associating lectin 1; MDL-1; CLEC5A; CLECSF5, MDL1;

Gene Name

CLEC5A

UniProt

Q9NY25

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Tissue Specificity

Highly expressed in bone marrow with lower levels in synovium, lung and bronchus (PubMed:20212065) . Expressed in peripheral blood monocytes and in the monocyte/macrophage cell lines U-937 and Mono-Mac-6, but not in cell lines of other origins (PubMed:10449773) . Expression is down-regulated when monocytes differentiate into dendritic cells (PubMed:10449773) .

Applications

WB, ELISA

Purification

CLC5A antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

Functions as a positive regulator of osteoclastogenesis (By similarity) . Cell surface receptor that signals via TYROBP (PubMed:10449773) . Regulates inflammatory responses (By similarity) .

Molecular Weight

21521 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

C-type lectin domain family 5 member A

Subcellular Location

Cell membrane

Protein Name

C-type lectin domain family 5 member A

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