Anti-R-spondin-2 RSPO2 Antibody
Boster Bio Anti-R-spondin-2 RSPO2 Antibody catalog # A05081. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
R-spondin-2; Roof plate-specific spondin-2; hRspo2; RSPO2; UNQ9384/PRO34209;
Gene Name
RSPO2
UniProt
Q6UXX9
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Applications
WB, ELISA
Purification
RSPO2 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Form
Liquid
Function
Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Probably also acts as a ligand for frizzled and LRP receptors.
Molecular Weight
28315 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
R-spondin-2
Subcellular Location
Secreted .
Protein Name
R-spondin-2
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