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Anti-R-spondin-2 RSPO2 Antibody

Boster Bio Anti-R-spondin-2 RSPO2 Antibody catalog # A05081. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

R-spondin-2; Roof plate-specific spondin-2; hRspo2; RSPO2; UNQ9384/PRO34209;

Gene Name

RSPO2

UniProt

Q6UXX9

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Applications

WB, ELISA

Purification

RSPO2 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Probably also acts as a ligand for frizzled and LRP receptors.

Molecular Weight

28315 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A05081

Product MSDS

https://www.bosterbio.com/msds?sku=A05081

Fragment

IgG

Other Gene Names

R-spondin-2

Subcellular Location

Secreted .

Protein Name

R-spondin-2

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