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Anti-Sperm-associated antigen 8 SPAG8 Antibody

Boster Bio Anti-Sperm-associated antigen 8 SPAG8 Antibody catalog # A10518-1. Tested in ELISA, WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

Sperm-associated antigen 8; HSD-1; Sperm membrane protein 1; SMP-1; Sperm membrane protein BS-84; SPAG8;

Gene Name

SPAG8

UniProt

Q99932

Host

Rabbit

Reactivity

Human

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Tissue Specificity

Expressed in testis (germ cells), but not in liver, kidney, prostate and small intestine.

Applications

WB, ELISA

Purification

SPAG8 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

Plays a role in spermatogenesis by enhancing the binding of CREM isoform tau to its coactivator FHL5 and increasing the FHL5-regulated transcriptional activation of CREM isoform tau (By similarity) . Involved in the acrosome reaction and in binding of sperm to the zona pellucida (By similarity) . Plays a role in regulation of the cell cycle by controlling progression through the G2/M phase, possibly by delaying the activation of CDK1 which is required for entry into mitosis (PubMed:19548270) . May play a role in fertility and microtubule formation through interaction with RANBP9 (PubMed:10500252) .

Molecular Weight

44819 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Sperm-associated antigen 8

Subcellular Location

Cytoplasm

Protein Name

Sperm-associated antigen 8

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