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Anti-TRIO Antibody

Boster Bio Anti-TRIO Antibody catalog # A00679. Tested in IHC applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Triple functional domain protein;2.7.11.1; PTPRF-interacting protein; TRIO;

Gene Name

TRIO

UniProt

O75962

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Tissue Specificity

Widely expressed, with highest levels in heart, skeletal muscle, and brain.

Applications

IHC

Purification

TRIO antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

IHC-p 1:50-300

Form

Liquid

Function

Guanine nucleotide exchange factor (GEF) for RHOA and RAC1 GTPases (PubMed:8643598, PubMed:27418539) . Involved in coordinating actin remodeling, which is necessary for cell migration and growth (PubMed:10341202) . In developing hippocampal neurons, limits dendrite formation, without affecting the establishment of axon polarity. Once dendrites are formed, involved in the control of synaptic function by regulating the endocytosis of AMPA-selective glutamate receptors (AMPARs) at CA1 excitatory synapses (By similarity) . May act as a regulator of adipogenesis (By similarity) .

Molecular Weight

346900 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Triple functional domain protein

Subcellular Location

Cytoplasm

Protein Name

Triple functional domain protein

Frequently Asked Questions

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