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Anti-CLK3 Antibody

Boster Bio Anti-CLK3 Antibody catalog # A08930. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Dual specificity protein kinase CLK3;2.7.12.1; CDC-like kinase 3; CLK3;

Gene Name

CLK3

UniProt

P49761

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Tissue Specificity

Endothelial cells.

Applications

WB, ELISA

Purification

CLK3 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause redistribution of SR proteins from speckles to a diffuse nucleoplasmic distribution. Phosphorylates SRSF1 and SRSF3. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells.

Molecular Weight

73515 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Dual specificity protein kinase CLK3

Subcellular Location

Isoform 1: Nucleus. Cytoplasm . Cytoplasmic vesicle, secretory vesicle, acrosome .

Protein Name

Dual specificity protein kinase CLK3

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