Anti-ALKB5 ALKBH5 Antibody
Boster Bio Anti-ALKB5 ALKBH5 Antibody catalog # A03360-1. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
RNA demethylase ALKBH5
Gene Name
ALKBH5
UniProt
Q6P6C2
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Tissue Specificity
Widely expressed, with highest expression in lung, followed by testis, pancreas, spleen and ovary.
Applications
WB, ELISA
Purification
ALKB5 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Form
Liquid
Function
Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N (6) -methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes (PubMed:23177736, PubMed:24778178, PubMed:24616105, PubMed:24489119) . Can also demethylate N (6) - methyladenosine in single-stranded DNA (in vitro) (PubMed:24616105) . Requires molecular oxygen, alpha-ketoglutarate and iron (PubMed:21264265, PubMed:23177736, PubMed:24778178, PubMed:24616105, PubMed:24489119) . Demethylation of m6A mRNA affects mRNA processing and export (PubMed:23177736) . Required for spermatogenesis (By similarity) .
Molecular Weight
44256 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
RNA demethylase ALKBH5
Subcellular Location
Nucleus speckle
Protein Name
RNA demethylase ALKBH5
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