Anti-PK1IP PAK1IP1 Antibody
Boster Bio Anti-PK1IP PAK1IP1 Antibody catalog # A11607. Tested in ELISA, WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
P21-activated protein kinase-interacting protein 1; PAK/PLC-interacting protein 1; hPIP1; PAK1-interacting protein 1; WD repeat-containing protein 84; PAK1IP1; PIP1, WDR84;
Gene Name
PAK1IP1
UniProt
Q9NWT1
Host
Rabbit
Reactivity
Human
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Applications
WB, ELISA
Purification
PK1IP antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Form
Liquid
Function
Negatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which has been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N-terminal regulatory domain. PAK1IP1 also binds to the N-terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42. May be involved in ribosomal large subunit assembly (PubMed:24120868) .
Molecular Weight
43964 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
P21-activated protein kinase-interacting protein 1
Subcellular Location
Nucleus, nucleolus
Protein Name
P21-activated protein kinase-interacting protein 1
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