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Anti-I12R2 IL12RB2 Antibody

Boster Bio Anti-I12R2 IL12RB2 Antibody catalog # A03189. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Interleukin-12 receptor subunit beta-2; IL-12 receptor subunit beta-2; IL-12R subunit beta-2; IL-12R-beta-2; IL-12RB2; IL12RB2;

Gene Name

IL12RB2

UniProt

Q99665

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from human protein at AA range: 270-350

Clonality

Polyclonal

Tissue Specificity

Isoform 2 is expressed at similar levels in both naive and activated T-cells.

Applications

WB, ELISA

Purification

I12R2 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

Receptor for interleukin-12. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. Promotes the proliferation of T-cells as well as NK cells. Induces the promotion of T-cells towards the Th1 phenotype by strongly enhancing IFN-gamma production.

Molecular Weight

97135 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Interleukin-12 receptor subunit beta-2

Subcellular Location

Membrane; Single-pass type I membrane protein.

Protein Name

Interleukin-12 receptor subunit beta-2

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