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Anti-ASPM Antibody

Boster Bio Anti-ASPM Antibody catalog # A02584. Tested in IHC applications. This antibody reacts with Human.

Product Specifications

Synonyms

Abnormal spindle-like microcephaly-associated protein; Abnormal spindle protein homolog; Asp homolog; ASPM; MCPH5;

Gene Name

ASPM

UniProt

Q8IZT6

Host

Rabbit

Reactivity

Human

Immunogen

Synthesized peptide derived from human protein at AA range: 1230-1310

Clonality

Polyclonal

Applications

IHC

Purification

ASPM antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

IHC-p 1:50-300

Form

Liquid

Function

Involved in mitotic spindle regulation and coordination of mitotic processes. The function in regulating microtubule dynamics at spindle poles including spindle orientation, astral microtubule density and poleward microtubule flux seems to depend on the association with the katanin complex formed by KATNA1 and KATNB1. Enhances the microtubule lattice severing activity of KATNA1 by recruiting the katanin complex to microtubules. Can block microtubule minus-end growth and reversely this function can be enhanced by the katanin complex (PubMed:28436967) . May have a preferential role in regulating neurogenesis.

Molecular Weight

409800 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Abnormal spindle-like microcephaly-associated protein

Subcellular Location

Cytoplasm . Cytoplasm, cytoskeleton, spindle

Protein Name

Abnormal spindle-like microcephaly-associated protein

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