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Anti-CAC1F CACNA1F Antibody

Boster Bio Anti-CAC1F CACNA1F Antibody catalog # A03442. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Voltage-dependent L-type calcium channel subunit alpha-1F ; Voltage-gated calcium channel subunit alpha Cav1.4; CACNA1F

Gene Name

CACNA1F

UniProt

O60840

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from human protein at AA range: 140-220

Clonality

Polyclonal

Tissue Specificity

Expression in skeletal muscle and retina (PubMed:10873387) . Isoform 4 is expressed in retina (PubMed:27226626) .

Applications

WB, ELISA

Purification

CAC1F antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

Isoform 1: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1F gives rise to L-type calcium currents. Long- lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, and by benzothiazepines. Activates at more negative voltages and does not undergo calcium-dependent inactivation (CDI), due to incoming calcium ions, during depolarization.

Molecular Weight

220678 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A03442

Product MSDS

https://www.bosterbio.com/msds?sku=A03442

Fragment

IgG

Other Gene Names

Voltage-dependent L-type calcium channel subunit alpha-1F

Subcellular Location

Membrane; Multi-pass membrane protein.

Protein Name

Voltage-dependent L-type calcium channel subunit alpha-1F

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