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Anti-UBP49 USP49 Antibody

Boster Bio Anti-UBP49 USP49 Antibody catalog # A12701. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Ubiquitin carboxyl-terminal hydrolase 49;3.4.19.12; Deubiquitinating enzyme 49; Ubiquitin thioesterase 49; Ubiquitin-specific-processing protease 49; USP49;

Gene Name

USP49

UniProt

Q70CQ1

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Applications

WB, ELISA

Purification

UBP49 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

Specifically deubiquitinates histone H2B at 'Lys-120' (H2BK120Ub) . H2BK120Ub is a specific tag for epigenetic transcriptional activation and acts as a regulator of mRNA splicing. Deubiquitination is required for efficient cotranscriptional splicing of a large set of exons.

Molecular Weight

79198 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Ubiquitin carboxyl-terminal hydrolase 49

Subcellular Location

Nucleus

Protein Name

Ubiquitin carboxyl-terminal hydrolase 49

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