Anti-UBP34 USP34 Antibody
Boster Bio Anti-UBP34 USP34 Antibody catalog # A08126. Tested in IHC applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Ubiquitin carboxyl-terminal hydrolase 34;3.4.19.12
Gene Name
USP34
UniProt
Q70CQ2
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Tissue Specificity
Expressed in brain at low level.
Applications
IHC
Purification
UBP34 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Dilution
IHC-p 1:50-300
Form
Liquid
Function
Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. Acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin (CTNBB1) -mediated transcription. Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
Molecular Weight
404233 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Ubiquitin carboxyl-terminal hydrolase 34
Protein Name
Ubiquitin carboxyl-terminal hydrolase 34
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