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Anti-TIP41-like protein TIPRL Antibody

Boster Bio Anti-TIP41-like protein TIPRL Antibody catalog # A08373. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

TIP41-like protein; Putative MAPK-activating protein PM10; Type 2A-interacting protein; TIP; TIPRL;

Gene Name

TIPRL

UniProt

O75663

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Applications

WB, ELISA

Purification

TIPRL antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

May be a allosteric regulator of serine/threonine- protein phosphatase 2A (PP2A) . Isoform 1 inhibits catalytic activity of the PP2A (D) core complex in vitro. The PP2A (C) :TIPRL complex does not show phosphatase activity. Acts as negative regulator of serine/threonine-protein phosphatase 4 probably by inhibiting the formation of the active PPP4C:PPP4R2 complex; the function is proposed to implicate it in DNA damage response by promoting H2AFX phosphorylated on Ser-140 (gamma-H2AFX) . May play a role in the regulation of ATM/ATR signaling pathway controlling DNA replication and repair.

Molecular Weight

31444 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

TIP41-like protein

Subcellular Location

Cytoplasm

Protein Name

TIP41-like protein

Frequently Asked Questions

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