Anti-Suppressor of IKBKE 1 SIKE1 Antibody
Boster Bio Anti-Suppressor of IKBKE 1 SIKE1 Antibody catalog # A14741. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Suppressor of IKBKE 1; Suppressor of IKK-epsilon; SIKE1; SIKE;
Gene Name
SIKE1
UniProt
Q9BRV8
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Tissue Specificity
Widely expressed. Expressed in brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, small intestine, placenta, lung and leukocytes. Present in all cell lines tested (at protein level) .
Applications
WB, ELISA
Purification
SIKE1 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Form
Liquid
Function
Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus- and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways.
Molecular Weight
23721 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Suppressor of IKBKE 1
Subcellular Location
Cytoplasm
Protein Name
Suppressor of IKBKE 1
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