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Anti-SPEG Antibody

Boster Bio Anti-SPEG Antibody catalog # A04825. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Striated muscle preferentially expressed protein kinase;2.7.11.1; Aortic preferentially expressed protein 1; APEG-1; SPEG; APEG1, KIAA1297;

Gene Name

SPEG

UniProt

Q15772

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Tissue Specificity

Isoform 1 is preferentially expressed in striated muscle. Non-kinase form such as isoform 3 is predominantly expressed in the aorta. Isoform 3 appears to be expressed only in highly differentiated ASMC in normal vessel walls and down-regulated in dedifferentiated ASMC in vivo. In response to vascular injuries ASMC dedifferentiate and change from a quiescent and contractile phenotype to a proliferative and synthetic phenotype. This proliferation of vascular smooth muscle cells is one of the most prominent features of atherosclerosis.

Applications

IHC

Purification

SPEG antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

IHC-p 1:50-300

Form

Liquid

Function

Isoform 3 may have a role in regulating the growth and differentiation of arterial smooth muscle cells.

Molecular Weight

354289 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A04825

Product MSDS

https://www.bosterbio.com/msds?sku=A04825

Fragment

IgG

Other Gene Names

Striated muscle preferentially expressed protein kinase

Subcellular Location

Isoform 3: Nucleus.

Protein Name

Striated muscle preferentially expressed protein kinase

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