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Anti-SCN3A Antibody

Boster Bio Anti-SCN3A Antibody catalog # A04569. Tested in ELISA, WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

Sodium channel protein type 3 subunit alpha; Sodium channel protein brain III subunit alpha; Sodium channel protein type III subunit alpha; Voltage-gated sodium channel subtype III; Voltage-gated sodium channel subunit alpha Nav1.3; SCN3A; KIAA1356, NAC3;

Gene Name

SCN3A

UniProt

Q9NY46

Host

Rabbit

Reactivity

Human

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Tissue Specificity

Expressed in enterochromaffin cells in both colon and small bowel (at protein level) .

Applications

WB, ELISA

Purification

SCN3A antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, forms a sodium-selective channel through which Na (+) ions may pass in accordance with their electrochemical gradient (PubMed:24157691, PubMed:28235671, PubMed:29466837) . May contribute to the regulation of serotonin/5-hydroxytryptamine release by enterochromaffin cells (By similarity) . In pancreatic endocrine cells, required for both glucagon and glucose-induced insulin secretion (By similarity) .

Molecular Weight

226294 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Sodium channel protein type 3 subunit alpha

Subcellular Location

Cell membrane

Protein Name

Sodium channel protein type 3 subunit alpha

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