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Anti-SPN90 NCKIPSD Antibody

Boster Bio Anti-SPN90 NCKIPSD Antibody catalog # A07992. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

NCK-interacting protein with SH3 domain;54 kDa VacA-interacting protein;54 kDa vimentin-interacting protein; VIP54;90 kDa SH3 protein interacting with Nck; AF3p21; Dia-interacting protein 1; DIP-1; Diaphanous protein-interacting protein; SH3 adapter protein SPIN90; WASP-interacting SH3-domain protein; WISH; Wiskott-Aldrich syndrome protein-interacting protein; NCKIPSD; AF3P21, SPIN90;

Gene Name

NCKIPSD

UniProt

Q9NZQ3

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Tissue Specificity

Highest expression in heart, brain, skeletal muscle, kidney and liver. Lower levels in placenta, lung, small intestine and leukocytes. Weak expression in colon, thymus and spleen.

Applications

WB, ELISA

Purification

SPN90 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

Has an important role in stress fiber formation induced by active diaphanous protein homolog 1 (DRF1) . Induces microspike formation, in vivo (By similarity) . In vitro, stimulates N-WASP- induced ARP2/3 complex activation in the absence of CDC42 (By similarity) . May play an important role in the maintenance of sarcomeres and/or in the assembly of myofibrils into sarcomeres. Implicated in regulation of actin polymerization and cell adhesion. Plays a role in angiogenesis.

Molecular Weight

78960 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A07992

Product MSDS

https://www.bosterbio.com/msds?sku=A07992

Fragment

IgG

Other Gene Names

NCK-interacting protein with SH3 domain

Subcellular Location

Nucleus. Colocalizes with DRF1 at membrane ruffles, and with Nck at Z-disks in mature cardiac myocytes.

Protein Name

NCK-interacting protein with SH3 domain

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