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Anti-NEK1 Antibody

Boster Bio Anti-NEK1 Antibody catalog # A04380. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Serine/threonine-protein kinase Nek1;2.7.11.1

Gene Name

NEK1

UniProt

Q96PY6

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from human protein at AA range: 280-360

Clonality

Polyclonal

Tissue Specificity

High fetal expression in the brain and kidney.

Applications

WB, ELISA

Purification

NEK1 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

Phosphorylates serines and threonines, but also appears to possess tyrosine kinase activity (PubMed:20230784) . Involved in DNA damage checkpoint control and for proper DNA damage repair (PubMed:20230784) . In response to injury that includes DNA damage, NEK1 phosphorylates VDAC1 to limit mitochondrial cell death (PubMed:20230784) . May be implicated in the control of meiosis (By similarity) . Involved in cilium assembly (PubMed:21211617) .

Molecular Weight

142828 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Serine/threonine-protein kinase Nek1

Subcellular Location

Nucleus

Protein Name

Serine/threonine-protein kinase Nek1

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