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Anti-PTPRK Antibody

Boster Bio Anti-PTPRK Antibody catalog # A05486. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Receptor-type tyrosine-protein phosphatase kappa; Protein-tyrosine phosphatase kappa; R-PTP-kappa;3.1.3.48; PTPRK; PTPK;

Gene Name

PTPRK

UniProt

Q15262

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from human protein at AA range: 180-260

Clonality

Polyclonal

Tissue Specificity

High levels in lung, brain and colon; less in liver, pancreas, stomach, kidney, placenta and mammary carcinoma.

Applications

WB, ELISA

Purification

PTPRK antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

Regulation of processes involving cell contact and adhesion such as growth control, tumor invasion, and metastasis. Negative regulator of EGFR signaling pathway. Forms complexes with beta-catenin and gamma-catenin/plakoglobin. Beta-catenin may be a substrate for the catalytic activity of PTPRK/PTP-kappa.

Molecular Weight

162102 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Receptor-type tyrosine-protein phosphatase kappa

Subcellular Location

Cell junction, adherens junction. Cell membrane; Single-pass type I membrane protein.

Protein Name

Receptor-type tyrosine-protein phosphatase kappa

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