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Anti-Neuroligin-1 NLGN1 Antibody

Boster Bio Anti-Neuroligin-1 NLGN1 Antibody catalog # A04948. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Neuroligin-1; NLGN1; KIAA1070;

Gene Name

NLGN1

UniProt

Q8N2Q7

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human protein at AA range: 410-490

Clonality

Polyclonal

Tissue Specificity

Expressed in the blood vessel walls (at protein level) . Detected in brain, and at lower levels in pancreas islet beta cells.

Applications

WB, ELISA

Purification

NLGN1 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses. Required to maintain wakefulness quality and normal synchrony of cerebral cortex activity during wakefulness and sleep.

Molecular Weight

93835 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A04948

Product MSDS

https://www.bosterbio.com/msds?sku=A04948

Fragment

IgG

Other Gene Names

Neuroligin-1

Subcellular Location

Cell membrane ; Single-pass type I membrane protein . Cell junction, synapse . Cell junction, synapse, postsynaptic cell membrane, postsynaptic density . Enriched in synaptic plasma membranes and clustered in synaptic clefts and postsynaptic densities. Detected at dendritic spines. Colocalized with DLG4/PSD-95 and GRIN1/NMDAR1 (By similarity) . .

Protein Name

Neuroligin-1

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