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Anti-CHL1 Antibody

Boster Bio Anti-CHL1 Antibody catalog # A03912. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Neural cell adhesion molecule L1-like protein; Close homolog of L1; Processed neural cell adhesion molecule L1-like protein; CHL1; CALL;

Gene Name

CHL1

UniProt

O00533

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from human protein at AA range: 140-220

Clonality

Polyclonal

Tissue Specificity

Expressed in the fetal and adult brain as well as in Schwann cell culture. Also detected in adult peripheral tissues.

Applications

WB, ELISA

Purification

CHL1 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

Extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity. Both soluble and membranous forms promote neurite outgrowth of cerebellar and hippocampal neurons and suppress neuronal cell death. Plays a role in neuronal positioning of pyramidal neurons and in regulation of both the number of interneurons and the efficacy of GABAergic synapses. May play a role in regulating cell migration in nerve regeneration and cortical development. Potentiates integrin-dependent cell migration towards extracellular matrix proteins. Recruits ANK3 to the plasma membrane (By similarity) . .

Molecular Weight

135071 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Neural cell adhesion molecule L1-like protein

Subcellular Location

Cell membrane ; Single-pass type I membrane protein . Soluble forms produced by cleavage/shedding also exist. .

Protein Name

Neural cell adhesion molecule L1-like protein

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