Anti-Netrin receptor UNC5D UNC5D Antibody

Receptor for the netrin NTN4 that promotes neuronal cell survival (By similarity) . Plays a role in cell-cell adhesion and cell guidance. Receptor for netrin involved in cell migration. Plays a role in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding (By similarity) . May play a role in apoptosis in response to DNA damage (PubMed:24691657) . It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (PubMed:24519068) . Mediates cell-cell adhesion via its interaction with FLRT3 on an adjacent cell (By similarity) .