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Anti-IRK13 KCNJ13 Antibody

Boster Bio Anti-IRK13 KCNJ13 Antibody catalog # A07163. Tested in ELISA, WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

Inward rectifier potassium channel 13; Inward rectifier K (+) channel Kir7.1; Potassium channel, inwardly rectifying subfamily J member 13; KCNJ13;

Gene Name

KCNJ13

UniProt

O60928

Host

Rabbit

Reactivity

Human

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Tissue Specificity

Predominantly expressed in small intestine. Expression is also detected in stomach, kidney, and all central nervous system regions tested with the exception of spinal cord.

Applications

WB, ELISA

Purification

IRK13 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ13 has a very low single channel conductance, low sensitivity to block by external barium and cesium, and no dependence of its inward rectification properties on the internal blocking particle magnesium.

Molecular Weight

40530 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Inward rectifier potassium channel 13

Subcellular Location

Membrane; Multi-pass membrane protein.

Protein Name

Inward rectifier potassium channel 13

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