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Anti-DMA HLA-DMA Antibody

Boster Bio Anti-DMA HLA-DMA Antibody catalog # A04878. Tested in ELISA, WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

HLA class II histocompatibility antigen, DM alpha chain; MHC class II antigen DMA; Really interesting new gene 6 protein; HLA-DMA; DMA, RING6;

Gene Name

HLA-DMA

UniProt

P28067

Host

Rabbit

Reactivity

Human

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Applications

WB, ELISA

Purification

DMA antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

Plays a critical role in catalyzing the release of class II-associated invariant chain peptide (CLIP) from newly synthesized MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO.

Molecular Weight

29194 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

HLA class II histocompatibility antigen, DM alpha chain

Subcellular Location

Late endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Localizes to late endocytic compartment. Associates with lysosome membranes.

Protein Name

HLA class II histocompatibility antigen, DM alpha chain

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