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Anti-MCF2L Antibody

Boster Bio Anti-MCF2L Antibody catalog # A08460. Tested in ELISA, WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

Guanine nucleotide exchange factor DBS; DBL's big sister; MCF2-transforming sequence-like protein; MCF2L; KIAA0362, OST

Gene Name

MCF2L

UniProt

O15068

Host

Rabbit

Reactivity

Human

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Applications

WB, ELISA

Purification

MCF2L antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

Guanine nucleotide exchange factor that catalyzes guanine nucleotide exchange on RHOA and CDC42, and thereby contributes to the regulation of RHOA and CDC42 signaling pathways (By similarity) . Seems to lack activity with RAC1. Becomes activated and highly tumorigenic by truncation of the N-terminus (By similarity) . Isoform 5 activates CDC42 (PubMed:15157669) .

Molecular Weight

128109 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Guanine nucleotide exchange factor DBS

Subcellular Location

Isoform 5: Cytoplasm

Protein Name

Guanine nucleotide exchange factor DBS

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