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Anti-GTP cyclohydrolase 1 GCH1 Antibody

Boster Bio Anti-GTP cyclohydrolase 1 GCH1 Antibody catalog # A01210. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

GTP cyclohydrolase 1;3.5.4.16

Gene Name

GCH1

UniProt

P30793

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Tissue Specificity

In epidermis, expressed predominantly in basal undifferentiated keratinocytes and in some but not all melanocytes (at protein level) .

Applications

WB, ELISA

Purification

GCH1 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

Positively regulates nitric oxide synthesis in umbilical vein endothelial cells (HUVECs) . May be involved in dopamine synthesis. May modify pain sensitivity and persistence. Isoform GCH-1 is the functional enzyme, the potential function of the enzymatically inactive isoforms remains unknown.

Molecular Weight

27903 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

GTP cyclohydrolase 1

Subcellular Location

Cytoplasm

Protein Name

GTP cyclohydrolase 1

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