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Anti-Folate receptor beta FOLR2 Antibody

Boster Bio Anti-Folate receptor beta FOLR2 Antibody catalog # A04574. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Folate receptor beta; FR-beta; Folate receptor 2; Folate receptor, fetal/placental; Placental folate-binding protein; FBP; FOLR2;

Gene Name

FOLR2

UniProt

P14207

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Tissue Specificity

Expressed in placenta and hematopoietic cells. Expression is increased in malignant tissues.

Applications

WB, ELISA

Purification

FOLR2 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release.

Molecular Weight

29280 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Folate receptor beta

Subcellular Location

Cell membrane; Lipid-anchor, GPI-anchor. Secreted .

Protein Name

Folate receptor beta

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