Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-ZNRF1 Antibody

Boster Bio Anti-ZNRF1 Antibody catalog # A10050. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

E3 ubiquitin-protein ligase ZNRF1;2.3.2.27; Nerve injury-induced gene 283 protein; RING-type E3 ubiquitin transferase ZNRF1; Zinc/RING finger protein 1; ZNRF1; NIN283;

Gene Name

ZNRF1

UniProt

Q8ND25

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Tissue Specificity

Expressed primarily in the nervous system, with expression higher in developing brain relative to adult. Expressed at low levels in testis and thymus.

Applications

WB, ELISA

Purification

ZNRF1 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

E3 ubiquitin-protein ligase that mediates the ubiquitination of AKT1 and GLUL, thereby playing a role in neuron cells differentiation. Plays a role in the establishment and maintenance of neuronal transmission and plasticity. Regulates Schwann cells differentiation by mediating ubiquitination of GLUL. Promotes neurodegeneration by mediating 'Lys-48'-linked polyubiquitination and subsequent degradation of AKT1 in axons: degradation of AKT1 prevents AKT1-mediated phosphorylation of GSK3B, leading to GSK3B activation and phosphorylation of DPYSL2/CRMP2 followed by destabilization of microtubule assembly in axons (Probable) .

Molecular Weight

23783 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

E3 ubiquitin-protein ligase ZNRF1

Subcellular Location

Endosome. Lysosome. Membrane; Peripheral membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Peripheral membrane protein . Associated with synaptic vesicle membranes in neurons.

Protein Name

E3 ubiquitin-protein ligase ZNRF1

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

RN5S481 Adenovirus (Human)
40075051 1.0 mL

RN5S481 Adenovirus (Human)

Sign In for Pricing
View Details
CBX5 Antibody
orb518693-01 50 μL

CBX5 Antibody

Sign In for Pricing
View Details
CBX5 Antibody
orb518693-02 100 µL

CBX5 Antibody

Sign In for Pricing
View Details
Lentiviral mouse Gbp3 shRNA (UAS) - Lentiviral mouse Gbp3 shRNA (UAS) (25)
GTR15303800 1 Vial

Lentiviral mouse Gbp3 shRNA (UAS) - Lentiviral mouse Gbp3 shRNA (UAS) (25)

Sign In for Pricing
View Details
DCTD Antibody
orb1286021 100 µL

DCTD Antibody

Sign In for Pricing
View Details
Goat Polyclonal Goat F(ab')2 anti-Mouse IgG (H+L) Secondary Antibody (Pre-absorbed)
NBP1-75168 1 mg

Goat Polyclonal Goat F(ab')2 anti-Mouse IgG (H+L) Secondary Antibody (Pre-absorbed)

Sign In for Pricing
View Details