What is the catalog number for Anti-HECW1 Antibody?

The catalog number for Anti-HECW1 Antibody is A11214.

What sizes are available for Anti-HECW1 Antibody?

Anti-HECW1 Antibody is available in the following size(s): 100 µL.

Is Anti-HECW1 Antibody in stock?

Anti-HECW1 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-HECW1 Antibody?

The safety data sheet for Anti-HECW1 Antibody is available here: https://www.bosterbio.com/msds?sku=A11214.

Anti-HECW1 Antibody

Boster Bio Anti-HECW1 Antibody catalog # A11214. Tested in ELISA, WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

E3 ubiquitin-protein ligase HECW1;2.3.2.26; HECT, C2 and WW domain-containing protein 1; HECT-type E3 ubiquitin transferase HECW1; NEDD4-like E3 ubiquitin-protein ligase 1; hNEDL1; HECW1; KIAA0322, NEDL1;

Gene Name

HECW1

UniProt

Q76N89

Host

Rabbit

Reactivity

Human

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Tissue Specificity

Predominantly expressed in neurons of adult and fetal brain. Weakly expressed in the kidney.

Applications

WB, ELISA

Purification

HECW1 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS) . Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.