Anti-CNGB3 Antibody

Boster Bio Anti-CNGB3 Antibody catalog # A04385. Tested in ELISA, WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

Cyclic nucleotide-gated cation channel beta-3; Cone photoreceptor cGMP-gated channel subunit beta; Cyclic nucleotide-gated cation channel modulatory subunit; Cyclic nucleotide-gated channel beta-3; CNG channel beta-3; CNGB3;

Gene Name

CNGB3

UniProt

Q9NQW8

Host

Rabbit

Reactivity

Human

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Tissue Specificity

Expressed specifically in the retina.

Applications

WB, ELISA

Purification

CNGB3 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cGMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficiency of the channel when coexpressed with CNGA3 (By similarity) . Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones.