Glycyrin
Product Specifications
UNSPSC Description
Glycyrin is a PPAR-γ ligand of licorice. Glycyrin can decrease the blood glucose levels of genetically diabetic mice. Glycyrin also shows antibacterial activity[1][2][3].
Target Antigen
Bacterial; PPAR
Type
Natural Products
Related Pathways
Anti-infection;Cell Cycle/DNA Damage;Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Infection; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/glycyrin.html
Solubility
10 mM in DMSO
Smiles
O=C1C(C2=CC=C(O)C=C2O)=CC3=C(OC)C(C/C=C(C)\C)=C(OC)C=C3O1
Molecular Weight
382.41
References & Citations
[1]Kuroda M,et, al. Phenolics with PPAR-gamma ligand-binding activity obtained from licorice (Glycyrrhiza uralensis roots) and ameliorative effects of glycyrin on genetically diabetic KK-A(y) mice. Bioorg Med Chem Lett. 2003 Dec 15;13(24):4267-72. |[2]Tanaka Y, et, al. Antibacterial compounds of licorice against upper airway respiratory tract pathogens. J Nutr Sci Vitaminol (Tokyo). 2001 Jun;47(3):270-3.|[3]Wang Q, et, al. Metabolites identification of glycyrin and glycyrol, bioactive coumarins from licorice. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Mar 1:983-984:39-46.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N3960/Glycyrin-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N3960/
Clinical Information
No Development Reported
CAS Number
66056-18-6
Available Sizes
Curated Selection
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