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Anti-CHSTE CHST14 Antibody

Boster Bio Anti-CHSTE CHST14 Antibody catalog # A07651. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Carbohydrate sulfotransferase 14;2.8.2.35; Dermatan 4-sulfotransferase 1; D4ST-1; hD4ST1; CHST14; D4ST1; UNQ1925/PRO4400;

Gene Name

CHST14

UniProt

Q8NCH0

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Tissue Specificity

Widely expressed. Expressed at high level in pituitary gland, placenta, uterus and thyroid.

Applications

WB, ELISA

Purification

CHSTE antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of dermatan sulfate. Plays a pivotal role in the formation of 4-0-sulfated IdoA blocks in dermatan sulfate. Transfers sulfate to the C-4 hydroxyl of beta1,4-linked GalNAc that is substituted with an alpha-linked iduronic acid (IdoUA) at the C-3 hydroxyl. Transfers sulfate more efficiently to GalNAc residues in -IdoUA-GalNAc-IdoUA- than in -GlcUA-GalNAc-GlcUA-sequences. Has preference for partially desulfated dermatan sulfate. Addition of sulfate to GalNAc may occur immediately after epimerization of GlcUA to IdoUA. Appears to have an important role in the formation of the cerebellar neural network during postnatal brain development.

Molecular Weight

42997 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Carbohydrate sulfotransferase 14

Subcellular Location

Golgi apparatus membrane ; Single-pass type II membrane protein .

Protein Name

Carbohydrate sulfotransferase 14

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