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Anti-IRK14 KCNJ14 Antibody

Boster Bio Anti-IRK14 KCNJ14 Antibody catalog # A13586. Tested in ELISA, WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

ATP-sensitive inward rectifier potassium channel 14; Inward rectifier K (+) channel Kir2.4; IRK-4; Potassium channel, inwardly rectifying subfamily J member 14; KCNJ14; IRK4;

Gene Name

KCNJ14

UniProt

Q9UNX9

Host

Rabbit

Reactivity

Human

Immunogen

Synthesized peptide derived from human protein at AA range: 350-430

Clonality

Polyclonal

Tissue Specificity

Expressed preferentially in retina.

Applications

WB, ELISA

Purification

IRK14 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ14 gives rise to low-conductance channels with a low affinity to the channel blockers Barium and Cesium (By similarity) . .

Molecular Weight

47846 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

ATP-sensitive inward rectifier potassium channel 14

Subcellular Location

Membrane; Multi-pass membrane protein.

Protein Name

ATP-sensitive inward rectifier potassium channel 14

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