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Anti-ABCG5 Antibody

Boster Bio Anti-ABCG5 Antibody catalog # A01503. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

ATP-binding cassette sub-family G member 5; Sterolin-1; ABCG5;

Gene Name

ABCG5

UniProt

Q9H222

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human protein at AA range: 250-330

Clonality

Polyclonal

Tissue Specificity

Strongly expressed in the liver, lower levels in the small intestine and colon.

Applications

WB, ELISA

Purification

ABCG5 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

ABCG5 and ABCG8 form an obligate heterodimer that mediates Mg (2+) - and ATP-dependent sterol transport across the cell membrane (PubMed:27144356) . Plays an essential role in the selective transport of dietary plant sterols and cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile (PubMed:11099417, PubMed:11138003, PubMed:27144356, PubMed:15054092) . Required for normal sterol homeostasis (PubMed:11099417, PubMed:11138003, PubMed:15054092) . The heterodimer with ABCG8 has ATPase activity (PubMed:16893193, PubMed:20210363, PubMed:27144356) .

Molecular Weight

72504 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

ATP-binding cassette sub-family G member 5

Subcellular Location

Cell membrane

Protein Name

ATP-binding cassette sub-family G member 5

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