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Anti-AT7L3 ATXN7L3 Antibody

Boster Bio Anti-AT7L3 ATXN7L3 Antibody catalog # A09382. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Ataxin-7-like protein 3

Gene Name

ATXN7L3

UniProt

Q14CW9

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from human protein at AA range: 40-120

Clonality

Polyclonal

Applications

WB, ELISA

Purification

AT7L3 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B (PubMed:18206972, PubMed:21746879) . The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex (PubMed:18206972) . Regulates H2B monoubiquitination (H2Bub1) levels. Affects subcellular distribution of ENY2, USP22 and ATXN7L3B (PubMed:27601583) .

Molecular Weight

38651 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A09382

Product MSDS

https://www.bosterbio.com/msds?sku=A09382

Fragment

IgG

Other Gene Names

Ataxin-7-like protein 3

Subcellular Location

Nucleus

Protein Name

Ataxin-7-like protein 3

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