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Anti-AWAT2 Antibody

Boster Bio Anti-AWAT2 Antibody catalog # A12143. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Acyl-CoA wax alcohol acyltransferase 2;2.3.1.75; Acyl-CoA retinol O-fatty-acyltransferase; ARAT; Retinol O-fatty-acyltransferase;2.3.1.76; Diacylglycerol O-acyltransferase 2-like protein 4; Diacylglycerol O-acyltransferase candidate 4; hDC4; Long-chain-alcohol O-fatty-acyltransferase 2; Multifunctional O-acyltransferase; Wax synthase; hWS; AWAT2; DC4, DGAT2L4, MFAT, WS;

Gene Name

AWAT2

UniProt

Q6E213

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from human protein at AA range: 260-340

Clonality

Polyclonal

Tissue Specificity

Abundant in tissues rich in sebaceous glands such as the preputial gland and eyelid. Highly expressed in skin, where it is primarily restricted to undifferentiated peripheral sebocytes. Also expressed at lower level in other tissues except pancreas.

Applications

WB, ELISA

Purification

AWAT2 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

Acyltransferase that predominantly esterify long chain (wax) alcohols with acyl-CoA-derived fatty acids to produce wax esters. Wax esters are enriched in sebum, suggesting that it plays a central role in lipid metabolism in skin. Has no activity using decyl alcohol and significantly prefers the C16 and C18 alcohols. May also have 2-acylglycerol O-acyltransferase (MGAT) and acyl- CoA:retinol acyltransferase (ARAT) activities, to catalyze the synthesis of diacylglycerols and retinyl esters; however this activity is unclear in vivo.

Molecular Weight

38094 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A12143

Product MSDS

https://www.bosterbio.com/msds?sku=A12143

Fragment

IgG

Other Gene Names

Acyl-CoA wax alcohol acyltransferase 2

Subcellular Location

Endoplasmic reticulum membrane

Protein Name

Acyl-CoA wax alcohol acyltransferase 2

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