Anti-NCYM MYCNOS Antibody
Boster Bio Anti-NCYM MYCNOS Antibody catalog # A13253. Tested in ELISA, WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
N-cym protein; N-myc opposite strand; MYCNOS; CYMN, NCYM;
Gene Name
MYCNOS
UniProt
P40205
Host
Rabbit
Reactivity
Human
Immunogen
Synthesized peptide derived from human NCYM protein.
Clonality
Polyclonal
Tissue Specificity
Expressed in the neuronal cells of the cerebrum and cerebellum, spermatocytes of the testis, pancreatic cells and also the heart. Expressed in both primary and metastatic neuroblastomas and in thyroid tumors (at protein level) . Expression is associated with poor prognosis in neuroblastoma. Expressed in the fetal brain, lung, liver and kidney at varying low levels.
Applications
WB, ELISA
Purification
NCYM antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Form
Liquid
Function
Regulates stability of MYCN in neuroblastoma cells by inhibiting GSK3B-mediated MYCN phosphorylation. Inhibits GSK3B activity by promoting its phosphorylation at 'Ser-9' (PubMed:24391509) .
Molecular Weight
11733 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
N-cym protein
Subcellular Location
Cytoplasm
Protein Name
N-cym protein
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