Anti-Elongin-B ELOB Antibody
Boster Bio Anti-Elongin-B ELOB Antibody catalog # A31718-1. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Elongin-B; EloB; Elongin 18 kDa subunit; RNA polymerase II transcription factor SIII subunit B; SIII p18; Transcription elongation factor B polypeptide 2; ELOB
Gene Name
ELOB
UniProt
Q15370
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from human protein at AA range: 30-110
Clonality
Polyclonal
Applications
WB, ELISA
Purification
ELOB antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Form
Liquid
Function
SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex) (PubMed:7638163) . In embryonic stem cells, the elongin BC complex is recruited by EPOP to Polycomb group (PcG) target genes in order generate genomic region that display both active and repressive chromatin properties, an important feature of pluripotent stem cells (By similarity) .
Molecular Weight
13133 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Elongin-B
Subcellular Location
Nucleus .
Protein Name
Elongin-B
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