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Anti-NFAT activation molecule 1 NFAM1 Antibody

Boster Bio Anti-NFAT activation molecule 1 NFAM1 Antibody catalog # A10383. Tested in ELISA, WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

NFAT activation molecule 1; Calcineurin/NFAT-activating ITAM-containing protein; NFAT-activating protein with ITAM motif 1; NFAM1; CNAIP;

Gene Name

NFAM1

UniProt

Q8NET5

Host

Rabbit

Reactivity

Human

Immunogen

Synthesized peptide derived from human protein at AA range: 30-110

Clonality

Polyclonal

Tissue Specificity

Highly expressed in neutrophils, primary monocytes, mast cells, monocytic cell lines and lymphocytes. Also expressed in spleen B and T-cells, and lung. Expressed at low level in non-immune tissue.

Applications

WB, ELISA

Purification

NFAM1 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

May function in immune system as a receptor which activates via the calcineurin/NFAT-signaling pathway the downstream cytokine gene promoters. Activates the transcription of IL-13 and TNF-alpha promoters. May be involved in the regulation of B-cell, but not T-cell, development. Overexpression activates downstream effectors without ligand binding or antibody cross- linking.

Molecular Weight

29686 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

NFAT activation molecule 1

Subcellular Location

Cell membrane ; Single-pass type I membrane protein . Partially recruited to lipid rafts upon BCR stimulation. .

Protein Name

NFAT activation molecule 1

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